FITC标记的微管相关蛋白9抗体-抗体-抗体-生物在线
上海沪震实业有限公司
FITC标记的微管相关蛋白9抗体

FITC标记的微管相关蛋白9抗体

商家询价

产品名称: FITC标记的微管相关蛋白9抗体

英文名称: Anti-MAP-9/FITC

产品编号: HZ-9313R-FITC

产品价格: null

产品产地: 中国/上海

品牌商标: HZbscience

更新时间: 2023-08-17T10:24:20

使用范围: IF=1:50-200

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 Rabbit Anti-MAP-9/FITC Conjugated antibody

FITC标记的微管相关蛋白9抗体

 

产品编号 bs-9313R-FITC
英文名称 Anti-MAP-9/FITC
中文名称 FITC标记的微管相关蛋白9抗体
别    名 ASAP; Aster associated protein; MAP9; MAP 9; microtubule associated protein 9; MAP9_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  信号转导  细胞周期蛋白  细胞分化  细胞骨架  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, 
产品应用 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 74kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human MAP-9
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Microtubules, the primary component of the cytoskeletal network, interact with proteins called microtubule-associated proteins (MAPs).MAP9 is a microtubule-associated protein required for spindle function, mitotic progression, and cytokinesis.The microtubule-associated proteins can be divided into two groups, structural and dynamic. The MAP proteins function to stimulate tubulin assembly, enhance microtubule stability, influence the spatial distribution of microtubules within cells and utilize microtubule polarity to translocate cellular components. MAP-9 (microtubule-associated protein 9), also known as ASAP, is a 647 amino acid cytoplasmic protein that is constitutively expressed during the cell cycle. MAP-9 localizes to microtubules in interphase, associates with the mitotic spindle during mitosis and localizes to the central body during cytokinesis. Involved in organization of the bipolar mitotic spindle, MAP-9 is required for bipolar spindle assembly, mitosis progression and cytokinesis. MAP-9 may be involved in stabilizing interphase microtubules. Two isoforms of MAP-9 are produced due to alternative splicing events.

Function:
Involved in organization of the bipolar mitotic spindle. Required for bipolar spindle assembly, mitosis progression and cytokinesis. May act by stabilizing interphase microtubules. 

Subunit:
Binds to purified microtubules via its C-terminus. 

Subcellular Location:
Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle. Note=Localizes to microtubules in interphase, associates with the mitotic spindle during mitosis, localizes to the central body during cytokinesis.

Database links:

Entrez Gene: 79884 Human

Omim: 610070 Human

SwissProt: Q49MG5 Human

Unigene: 61271 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications
   

微管是细胞骨架网络的主要成分,与被称为微管相关蛋白(MAP)的蛋白相互作用。MAP9是纺锤体功能、有丝分裂进程和胞质分裂所需的微管相关蛋白,微管相关蛋白可分为:两组,结构和动态。MAP蛋白的功能是刺激微管蛋白组装,增强微管稳定性,影响微管在细胞内的空间分布,并利用微管极性易位细胞组分。MAP9(微管相关蛋白9),也称为ASAP,是在细胞周期中组成性表达的647氨基酸胞质蛋白。MAP-9定位于间期的微管,在有丝分裂期间与有丝分裂纺锤体相关,并在胞质分裂时定位于中央体。在双极性有丝分裂纺锤体的组织中,MAP-9是双极纺锤体组装、有丝分裂进程和胞质分裂所必需的。MAP-9可能参与稳定相间微管的作用。MAP -9的两种异构体是由于选择性剪接事件产生的。