CIB1 monoclonal antibody, clone 5A1F5E12, 5A1H7E12
产品名称： CIB1 monoclonal antibody, clone 5A1F5E12, 5A1H7E12
英文名称： CIB1 monoclonal antibody, clone 5A1F5E12, 5A1H7E12
产品编号： MAB8297
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against partial recombinant CIB1.
- Immunogen:
- Recombinant protein corresponding to truncated human CIB1.
- Host:
- Mouse
- Reactivity:
- Human
- Form:
- Liquid
- Storage Buffer:
- In PBS, pH 7.2 (50% glycerol, 0.01% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Western Blot (1:500-1:2000)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:500-1:2000)
Immunohistochemistry (Frozen sections) (1:500-1:2000)
ELISA (1:10000)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- The interaction between calcium- and integrin-binding protein 1 and the alphaIIb integrin cytoplasmic domain involves a novel C-terminal displacement mechanism.
Yamniuk AP, Ishida H, Vogel HJ.J Biol Chem. 2006 Sep 8;281(36):26455-64. Epub 2006 Jul 6.
- 2.
- CIB1, a ubiquitously expressed Ca2+-binding protein ligand of the InsP3 receptor Ca2+ release channel.
White C, Yang J, Monteiro MJ, Foskett JK.J Biol Chem. 2006 Jul 28;281(30):20825-33. Epub 2006 May 24.
- 3.
- Structural and biochemical characterization of CIB1 delineates a new family of EF-hand-containing proteins.
Gentry HR, Singer AU, Betts L, Yang C, Ferrara JD, Sondek J, Parise LV.J Biol Chem. 2005 Mar 4;280(9):8407-15. Epub 2004 Dec 1.
- Applications
- Western Blot
- Western blot analysis using CIB1 monoclonal antibody, clone 5A1F5E12, 5A1H7E12 (Cat # MAB8297) against truncated CIB1 recombinant protein (Lane 1) and A-431 cell lysate (Lane 2).
- Entrez GeneID:
- 10519
- Gene Name:
- CIB1
- Gene Alias:
- CIB,KIP,KIP1,SIP2-28
- Gene Description:
- calcium and integrin binding 1 (calmyrin)
- Omim ID:
- 602293
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a member of the calcium-binding protein family. The specific function of this protein has not yet been determined; however this protein is known to interact with DNA-dependent protein kinase and may play a role in kinase-phosphatase regulation of DNA end joining. This protein also interacts with integrin alpha(IIb)beta(3), which may implicate this protein as a regulatory molecule for alpha(IIb)beta(3). [provided by RefSeq
- Other Designations:
- DNA-dependent protein kinase interacting protein,Snk interacting protein 2-28,calcium and integrin binding 1,calcium and integrin binding protein,calcium and integrin binding, protein kinase interacting protein,calmyrin
- Related Disease